Open Clinical Trials

Morriss R, Xydopoulos G, Craven M, Price L and Fordham R. Clinical effectiveness and cost minimisation model of Alpha-Stim cranial electrotherapy stimulation in treatment seeking patients with moderate to severe generalised anxiety disorder. J Affect Disord, 2019 Apr 15;253: 426-437.

Platoni K, Oakley R, Haltiwanger SG, et al. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression. Journal of Depression and Anxiety, 2019; 2(1): 006.

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachers. Journal of Depression and Anxiety, 2019; 8:334.

Morrow DJ, Fischer EP, Walder AM, Jubran NI. Nonopioid alternatives to addressing pain intensity: a retrospective look at two noninvasive pain treatment devices. Federal Practitioner, 2019;36(4): 181-187.

Graphic Summary of Alpha-Stim CES Pain Studies

Graphic Summary of Key Studies in Insomnia

Graphic Summary of Key Alpha-Stim CES Anxiety Studies

Graphic Summary of Alpha-Stim CES Depression Studies

Rickabaugh K, Johnson T, Martin S, Jones C and Onifer D. A retrospective review of patient perception of Alpha-Stimulation treatment. Poster presented at The Military Health System Symposium in Kissimmee, Florida. 2016; August 15-18.

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management. 2018, 55(2): 198–206.

Mellen, Ronald R., Case, Jan and Ruiz, Deanna J. Cranial electrotherapy stimulation (CES) As a treatment for reducing stress and improving prefrontal cortex functioning in victims of domestic violence. International Association for Correctional and Forensic Psychology Newsletter. 48(3):12-15, 2016

Lu XY, Wang AH, Li Y, Zhang JS, Liu BX. Safety and effectiveness of cranial electrotherapy stimulation in treating children with emotional disorders. Chinese Journal of Clinical Rehabilitation. 2005; 9(8):96-7

Smith, Ray B, et. al. The use of cranial electrotherapy stimulation to block fear perception in phobic patients. Journal of Current Therapeutic Research, 51(2):249-253, 1992

Overcash, Stephen J. Cranial electrotherapy stimulation in patients suffering from acute anxiety disorders. American Journal of Electromedicine, 16(1):49-51, 1999.

Kennerly, Richard. QEEG analysis of cranial electrotherapy: a pilot study. Journal of Neurotherapy (8)2, 2004. Presented at the International Society for Neuronal Regulation annual conference, September 18-21, 2003 in Houston, Texas

Kennerly, Richard. Changes in quantitative EEG and low resolution tomography following cranial electrotherapy stimulation. Ph.D. Dissertation, the University of North Texas. 529 pp., 81 tables, 233 figures, 171 references, 2006